The U.S.S. Enterprise-E has launched, with Captain Picard in command, but soon Picard is devastated to learn that there's a saboteur on board, in the form of a changeling infiltrator from the Dominion.
A Federation President sends Captain Picard to Deep Space Nine, to meet Chancellor Gowron. When their runabout is shot down, it's up to Commanders Worf and Data to find out the truth before their captains are killed.
The Enterprise is assigned to ferry demolition experts from Deep Space 9 to Starbase 375, but just as they arrive Admiral Leyton declares martial law on Earth and the Federation is put in a state of emergency.
A team from the Enterprise is sent to deal with the latest threat from the Maquis. For La Forge and Daniels, it's just another mission, but Riker must face the specter of his transporter twin, Tom Riker, who left Starfleet to join the Maquis.
Newly promoted Admiral Hayes gives La Forge a shocking ultimatum: his VISOR is a security risk, and he must either have it replaced with ocular implants or be transferred to a less-sensitive post. Meanwhile, Troi has some issues of her own.
In the wake of increased concern over the Dominion threat, Dr. Beverly Crusher has attempted to improve morale on the Enterprise by starting up her theater company, but before opening night a devastating malady starts striking down the crew.